Udenafil was launched in Korea in 2005 under the name Zydena. Like most major ED drugs taken orally, Udenafil is a PDE-5 inhibitor.

Zydena has been promoted as the ‘safe’ Erectile Dysfunction drug, with no recorded severe side effects such as blindness or heart problems. However as it has not been on the international market as long there is less research around the product.

Currently, Udenafil is not available outside Asia and Russia. It is unclear at what stage it will become available in Australia; it is likely it will be after FDA approval in the US, as has been the case with the other major erectile dysfunction drugs.


Udenafil is used for Erectile Dysfunction: the inability to attain or maintain an erection sufficient for sexual activity.

Like most erectile dysfunction drugs, Udenafil works by vasodilation, relaxing penile blood vessels during sexual arousal. This increases bloodflow, enhancing erectile function.

Udenafil does not increase libido, and only works if you are sexually excited. It only suitable for adult men and available only with prescription.

Action Onset and Duration

Udenafil seems to take about thirty minutes for its effects to be felt, although it claims to work much faster than Viagra. However there is little conclusive research available at the moment. It should probably be taken about an hour before sex.

Duration of effect is around 12 hours, although the manufacturers claim it will last up to 24 hours. There is not yet sufficient clinical evidence to support this claim however.


Standard dosage for Udenafil is 100mg. It is important to follow your doctor’s advice though; Never exceed recommended daily dosage. Take no more than once a day.

Side Effects

Headaches and facial flushing may be commonly experienced.

So far, Udenafil is not associated with any severe side effects. However, unlike Cialis, Levitra and Viagra, there is not a lot of comprehensive research on the effects of Udenafil yet. If you do experience any serious side effects, cease use immediately and see a doctor.


  1. If you are taking Nitrates for chest pain, angina, or any heart condition.
  2. If you’ve suffered heart attack or stroke in the last six months.
  3. If you’re affected by hypo- or hyper-tension.
  4. If you are taking Amyl Nitrate.
  5. If you suffer loss of vision due to Non-Arteric Anterior Ischaemic Optic Neuropathy (NAION).
  6. If you have known allergies to Udenafil or any of its constituents.


  • Tell your doctor if you are affected by any of the following:
  • Any heart or blood vessel problems
  • Any vision or hearing problems
  • Kidney and Liver problems
  • Sickle-Cell Anaemia

Also, avoid:

  • Grapefruit
  • Yohimbe

Drug Interactive Effects

The following medicines may interact with Udenafil and other ED drugs, rendering one or both of them ineffective:

  • Nitro-glycerin
  • Alpha-blockers
  • Isosorbide Dinitrate
  • Isosorbide Mononitrate

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